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Here is the sentence as sub transcribed: They really have not increased significantly in size, however, there was a question of a stone in her right kidney.
I think it should be either one of two ways:
They really have not increased significantly in size; however, there was a question of a stone in her right kidney. They really have not increased significantly in size. However, there was a question of a stone in her right kidney.
This is a new account (1 week) and a new sub. Playing the Devil's advocate this doc does tend to dictate run-on sentences. I really believe that the first comma as transcribed should really be a semi-colon or a period (starting new sentence). What do you think?