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proBNP - level
Posted: Nov 20, 2012
Having a major brain farct here:
Dictated "proBNP was thirty-seven five hundred and twenty-four"
How is this transcribed, not sure if its 37,524 or if this is 2 different numbers? Sorry just not thinking straight right now and google is of no assistance.
I believe this is a range so would be 37-524 - sm
[ In Reply To ..]BNP
Immunochemiluminometric assay (ICMA)
– Fully automated method (ADVIA Centaur®)
– Utilizes a capture antibody specific for the C-terminal end of BNP-32 and a detection antibody
specific for the intramolecular ring structure of BNP-32
– Bound BNP separated from free via streptavidin-coated magnetic particles
– Quantitation based on the relative light units (RLU) produced in a chemical reaction
Analytical sensitivity: 4 pg/mL
Analytical specificity: no cross-reactivity with ANP, CNP (7-28), or NT-proBNP (1-76)
Reportable range: 4 – 4200 pg/mL
Synonyms: brain natriuretic peptide; BNP
proBNP, N-terminal
Immuno(electro)chemiluminescence assay (ICMA)
– Utilizes two different polyclonal sheep NT-proBNP antibodies (one labeled with biotin and the other
labeled with ruthenium)
– Bound NT-proBNP separated from free via streptavidin-coated magnetic microparticles
– Quantitation based on the RLU produced in an electrochemical reaction between ruthenium and tri-
propylamine (TPA)
Analytical sensitivity: 10 pg/mL
Analytical specificity: no cross-reactivity with ANP, BNP, or CNP; no interference from hemoglobin (<1.4 g/dL), triglyceride (<4000 mg/dL), bilirubin (<35 mg/dL), biotin (<30 ng/dL), rheumatoid factors (<1500 IU/mL) or heterophilic antibodies
Reportable range: 10–35,000 pg/mL
Synonyms: NT-proBNP; N-terminal, pro-B-type natriuretic peptide; N-terminal, pro-brain natriuretic peptide; Elecsys® proBNP
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