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here is some more reading for you, all from google. - sm

Posted: Sep 13th, 2019 - 1:37 pm In Reply to: medial peripatellar osteophyte formations - Nik

Formation of Osteophytes
Technically speaking, an osteophyte is a fibrocartilage-capped bony outgrowth originating from precursor cells in the periosteum, the tissue that lines the bones and contains the cells that form new bone. Transforming growth factor β plays a role in their development.

An osteophyte develops when the remaining cartilage in a damaged joint attempts a repair after there is cartilage loss elsewhere in the joint. It tends to form in the joint compartment where there has been cartilage loss, suggesting it is a localized event. Osteophyte formation stabilizes the damaged joint.

That said, exactly how they form and what stimulates their formation is not completely understood. Osteophytes can also develop in the absence of explicit cartilage damage.

Location of Osteophyte Formation
Marginal osteophytes can develop at the periphery or margin of any joint. Central osteophytes are most prominent in the hip and knee.

Osteophytes also may be found in the spine region, where they are associated with back or neck pain and considered a common sign of degenerative arthritis (osteoarthritis).

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