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I'm on 20 mg weekly of the methotrexate, eight 2.5 mg tablets weekly. I take it on Thursday night about 7 pm, sleep through most of the fatigue portion side effects, then run to the bathroom most of the day on Friday with diarrhea and just plain feel sh***y, (needless to say my production is in the toilet on Fridays, how's that for a pun?) then by Saturday I am okay. I hate to take it on Saturday and blow my whole weekend not feeling great. Haven't lost my hair, but I did when I took cyclophosphamide for 2 years. In fact, my hair grows too much. I have short hair and need to be at the beauty shop pronto every 6 weeks for a cut. I do take folic acid and it does help with the mouth sores. I had thrush 4 times. YUK. Been doing this since off the prednisone and doc said I am a lifer for either methotrexate or prednisone. What fun, but at least I'm not sick anymore with severe headaches and all that other involvement I had. Have to take the good with the bad I guess. |