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I have major refractory depression and have taken about 20 different drugs for it because virtually none of them work on me. Sam-e worked GREAT for me but I had to take the top dose of 1600 mg a day and it was too expensive to maintain at that dosage. It only took me a few days to feel a radical change for the better, but everyone's chemistry is different. If you can afford it, I'd definitely give it a try. I had no side effects at all, either. St. John's Wort did nothing for me at all. |